Non-restorative sleep’s significance for those with fibromyalgia and CFS/ME


A large proportion of the population suffers from either Fibromyalgia Syndrome (FMS) or Chronic Fatigue Syndrome (CFS), both of which are multifactorial illnesses that may be debilitating. Many of the abnormal results, such fatigue, discomfort, sad mood, and memory problems, in those diagnosed with FMS or CFS are linked to inadequate sleep. The symptoms of these abnormalities include weariness, pain, and memory loss. We know there is a close relationship between sleep, pain, and fatigue, but what role does NRS play in the onset of these conditions? There are no non restorative sleep benifits, so you need to know the harms.

The NRS Hallmark Options for You

The hallmark of NRS is a lack of morning refreshment despite getting an adequate amount of sleep the night before. Electroencephalogram (EEG) arousals in non-REM sleep may also accompany NRS, along with impairment throughout the day, discomfort, fatigue, and sleep disruptions. Researchers began investigating NRS as a possible cause of FMS and CFS in the 1970s because to its high prevalence among people with these illnesses. The nocturnal awakening syndrome (NRS) is a common sign of intrinsic sleep disorders such sleep apnea, and a major cause of insomnia. Neurorestorative syndrome (NRS) is currently undiagnosed, has no established cause, and offers few viable therapy options; yet, it may help us better understand the role of sleep in the management of chronic pain and fatigue.

The Problem With the Lack of Sleep

The idea of NRS originated with the restorative sleep hypothesis, which states that when we sleep, our brains refill our physical and mental resources in preparation for the following day. This is supported by the fact that bone growth and skin regeneration occur more rapidly during sleep in both rats and humans. Mice and men alike. Humans have higher metabolic demands when they sleep for extended periods of time. Although we currently know more than ever before, NRS is still not fully understood or well defined in medical studies.

Patients diagnosed with FMS or CFS often report NRS as one of their primary symptoms

Participants with FMS who reported experiencing NRS made up 65.7% of the study population.1 One hundred percent of the study population reported experiencing “non-refreshing sleep,” compared to just 10% of the control group in a study that was quite comparable to this one.Patients with CFS have also been demonstrated to be 28 times more likely than healthy controls to report a positive response to an NRS-related component.3 Empirical evidence supports the hypothesis that FMS and CFS have a considerable connection with NRS; nevertheless, the lack of longitudinal data on this issue means that it is currently unknown whether NRS precedes or follows FMS/CFS. It is also hard to determine whether NRS would disappear if FMS or CFS were adequately treated since there is no one-size-fits-all treatment for these conditions.


FMS and CFS are only two examples of the many chronic conditions in which NRS plays a prominent role, along with fatigue, pain, cognitive function, and mood disorders. Despite NRS sometimes being confused with sleep fragmentation and sleep loss, its measurement remains challenging. More research is needed to provide a firm foundation for understanding the relationship between NRS and FMS/CFS. For the time being, getting the most restorative sleep possible requires adhering to certain fundamental principles of excellent sleep hygiene. Among these recommendations is maintaining a consistent routine and avoiding caffeine in the time leading up to bedtime.